Methanandamide

Methanandamide is a research chemical which is a derivative of anandamide (AEA). It is more stable and less lipid soluble than anandamide. Methanandamide is a selective agonist for the cannabinoid receptor type 1 (CB1). It has a similar binding affinity and potency as anandamide but has increased thermal stability and less susceptibility to enzymatic hydrolysis.

Chemistry

Methanandamide is a synthetic analog of anandamide with a methyl ester functional group added to the ethanolamine head of the molecule. This modification increases the stability of the molecule and its resistance to enzymatic hydrolysis.

Pharmacology

Methanandamide acts as a partial agonist at the CB1 receptor, with a similar potency to anandamide. It has been used in scientific research to investigate the role of the endocannabinoid system in various physiological processes.

Research

Methanandamide has been used in a variety of research contexts, including studies on pain, inflammation, and neuroprotection. It has also been used to investigate the potential therapeutic applications of cannabinoids in conditions such as multiple sclerosis, Parkinson's disease, and cancer.

See also

• Anandamide
• Cannabinoid receptor
• Endocannabinoid system

Methanandamide Resources
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