Methoxamine

From WikiMD's Food, Medicine & Wellness Encyclopedia

Methoxamine is a vasoconstrictor that is used in many medical treatments. It is a direct-acting alpha-adrenergic agonist that is used to treat hypotension and to maintain blood pressure during anesthesia.

Pharmacology[edit | edit source]

Methoxamine works by stimulating alpha-adrenergic receptors in the smooth muscle of blood vessels, which causes the vessels to constrict. This increases vascular resistance and raises blood pressure.

Uses[edit | edit source]

Methoxamine is used to treat hypotension, particularly in patients undergoing anesthesia. It is also used in some cases to treat orthostatic hypotension, a condition in which blood pressure falls when a person stands up.

Side Effects[edit | edit source]

Like all medications, methoxamine can cause side effects. These may include headache, palpitations, and chest pain. In rare cases, it can cause severe hypertension.

Contraindications[edit | edit source]

Methoxamine should not be used in patients with severe hypertension, pheochromocytoma, or coronary artery disease. It should also be used with caution in patients with prostatic hyperplasia or diabetes.

Interactions[edit | edit source]

Methoxamine can interact with other medications, including beta-blockers, antidepressants, and MAO inhibitors. These interactions can increase the risk of side effects and should be monitored closely by a healthcare provider.

See Also[edit | edit source]

Methoxamine Resources
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