Methylenedioxybenzylpiperazine

Methylenedioxybenzylpiperazine (MDBZP) is a psychoactive drug and research chemical of the piperazine class. It is closely related to benzylpiperazine (BZP). MDBZP has been sold as an ingredient in legal recreational drugs known as "Party pills", and is an analog of the controlled substance BZP.

Chemistry

MDBZP is a piperazine derivative which is a class of compounds that possess a broad range of pharmacological activities. It is structurally related to the anti-histamine buclizine. It is also structurally similar to the active component of black pepper, piperine, and to the anti-migraine drug pizotifen.

Pharmacology

The pharmacology of MDBZP is not fully understood. However, it is known that MDBZP has a similar mode of action to other piperazines such as BZP and TFMPP. It is believed to have empathogenic effects and to act as a serotonin and norepinephrine releasing agent.

Effects

The effects of MDBZP are similar to those of other recreational piperazines, and include euphoria, stimulation, enhanced appreciation for music, elevated mood, decreased hostility, improved mental function and mild hallucinations. However, it also has a number of negative side effects, including nausea, vomiting, insomnia, headache, dizziness, and in rare cases, seizures.

Legal Status

The legal status of MDBZP varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use. It is illegal to sell or supply MDBZP in many countries, including the United States, United Kingdom, Australia, and New Zealand.

See Also

• Benzylpiperazine
• Party pills
• Piperazine
• Psychoactive drug
• Research chemical