Methylenedioxyhydroxylmethamphetamine

From WikiMD's Food, Medicine & Wellness Encyclopedia

Methylenedioxyhydroxylmethamphetamine (MDHMA) is a psychoactive drug and a substituted amphetamine derivative. It is structurally related to 3,4-methylenedioxy-N-methylamphetamine (MDMA), a widely used recreational drug known commonly as ecstasy.

Chemistry[edit | edit source]

MDHMA is a ring-substituted amphetamine derivative, and it shares the core amphetamine structure. However, it differs from amphetamine due to the presence of a methylenedioxy group attached to the phenyl ring and a hydroxyl group attached to the alpha carbon.

Pharmacology[edit | edit source]

The pharmacological effects of MDHMA are not well-studied. However, it is believed to act as a serotonin-norepinephrine-dopamine releasing agent (SNDRA), similar to its structural analog, MDMA. This means it promotes the release of these neurotransmitters in the brain, which can lead to various psychological and physiological effects.

Effects[edit | edit source]

The effects of MDHMA are largely unknown due to the lack of scientific research. However, based on its structural similarity to MDMA, it is speculated that it may produce similar effects, such as feelings of euphoria, increased sociability, and altered sensory perception.

Legal Status[edit | edit source]

The legal status of MDHMA varies by country. In many jurisdictions, it is considered a controlled substance due to its structural similarity to MDMA.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD