Methylisopropyltryptamine

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Methylisopropyltryptamine (MiPT) is a psychedelic compound of the tryptamine family. It is a structural analog of N,N-dimethyltryptamine (DMT) and is known for its unique effects when compared to other tryptamines.

Chemistry[edit | edit source]

MiPT belongs to the tryptamine class of compounds, which are structurally similar to the amino acid tryptophan. It is a monoamine alkaloid that is substituted at the R4 position of the indole ring with an isopropyl group. The tryptamine molecule also has two methyl groups attached to the terminal amine RN of its tryptamine backbone (MiPT).

Pharmacology[edit | edit source]

The exact mechanism of action of MiPT is not fully understood. However, it is believed to work primarily by acting as an agonist for the serotonin 5-HT2A receptor, similar to other psychedelic tryptamines. It may also interact with other serotonin and dopamine receptors.

Effects[edit | edit source]

The effects of MiPT can vary greatly depending on the dose, set, and setting. Common effects reported by users include visual distortions, enhanced sensory perception, and changes in thought patterns and mood. Some users also report experiencing a unique 'tryptamine space' or 'headspace' characterized by complex, abstract thoughts and introspective insights.

Legal Status[edit | edit source]

The legal status of MiPT varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use.

Safety[edit | edit source]

As with all psychedelics, MiPT should be used with caution. It is recommended that users start with a low dose and gradually increase as they become more familiar with the effects. Users should also be aware of the potential for psychological dependence and the risk of experiencing a 'bad trip'.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD