Methylorubrum extorquens

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Methylorubrum extorquens is a species of bacteria belonging to the family Methylobacteriaceae. It is a facultative methylotroph, meaning it can grow by oxidizing single-carbon compounds such as methanol, as well as multi-carbon compounds, but does not require these for growth. This versatility allows M. extorquens to inhabit a wide range of environments, including soil, water, and plant surfaces. The bacterium is of particular interest in the fields of biotechnology and environmental science due to its ability to metabolize methanol, a compound that is both a waste product of plant metabolism and a significant component of some industrial waste streams.

Characteristics[edit | edit source]

Methylorubrum extorquens is a Gram-negative, rod-shaped bacterium. It is motile, using a single polar flagellum for movement. The cells can form pink colonies due to the presence of carotenoid pigments, which protect the bacteria from UV radiation. This bacterium is known for its metabolic flexibility, being able to switch between different sources of carbon depending on availability. It plays a significant role in the global carbon cycle by converting methanol into biomass and carbon dioxide.

Genetics[edit | edit source]

The genome of M. extorquens has been sequenced, revealing insights into its metabolic capabilities and environmental adaptations. The genome contains genes for both the serine cycle and the ethylmalonyl-CoA pathway, which are used for the assimilation of C1 compounds and multi-carbon compounds, respectively. This genetic makeup underpins the bacterium's metabolic versatility and its ability to thrive in diverse environments.

Ecology[edit | edit source]

Methylorubrum extorquens is commonly found in the phyllosphere, the aerial parts of plants, where it contributes to the degradation of methanol, a byproduct of plant growth. Its presence in the phyllosphere can influence plant health and growth, making it an organism of interest in agricultural research. Additionally, its ability to metabolize pollutants makes it a candidate for use in bioremediation projects aimed at cleaning up industrial waste streams containing methanol and other organic pollutants.

Applications[edit | edit source]

Due to its unique metabolic capabilities, Methylorubrum extorquens has potential applications in biotechnology. It has been studied for its ability to produce valuable chemicals from methanol, including amino acids, vitamins, and biopolymers. Furthermore, its role in carbon cycling and potential for bioremediation makes it a subject of environmental research, with the aim of developing sustainable technologies for waste treatment and greenhouse gas mitigation.

Research[edit | edit source]

Ongoing research on Methylorubrum extorquens focuses on understanding its metabolic pathways, genetic regulation, and ecological interactions. This knowledge is crucial for harnessing the bacterium's capabilities for industrial and environmental applications. Studies are also exploring the potential of genetic engineering to enhance its natural abilities or endow it with new functions, opening up possibilities for innovative uses in biotechnology.

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Contributors: Prab R. Tumpati, MD