Methylpiperidinopyrazole

Methylpiperidinopyrazole (MPP) is a synthetic, nonsteroidal estrogen receptor antagonist. It is often used in scientific research to study the role of estrogen receptors in the body. MPP is known for its high selectivity and potency, making it a valuable tool in the field of endocrinology and pharmacology.

Chemistry

Methylpiperidinopyrazole is a pyrazole derivative. Its chemical structure includes a pyrazole ring, a piperidine ring, and a methyl group. The presence of these functional groups contributes to its unique pharmacological properties.

Pharmacology

MPP acts as an antagonist at the estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). It binds to these receptors and blocks the action of estrogen, a hormone that plays a crucial role in many physiological processes. By blocking the action of estrogen, MPP can be used to study the effects of this hormone in the body.

Uses

In scientific research, MPP is often used to study the role of estrogen receptors in various diseases and conditions, including breast cancer, osteoporosis, and cardiovascular disease. It is also used in the development of new drugs that target estrogen receptors.

Safety

As a research chemical, MPP is not intended for human consumption. Its safety profile in humans is not well-studied. However, in animal studies, it has been shown to have low toxicity.

See also

• Estrogen receptor
• Endocrinology
• Pharmacology