Metronidazole benzoate

Metronidazole benzoate is a pharmaceutical drug used primarily in the treatment of infections caused by anaerobic bacteria and protozoa. It is a prodrug of metronidazole, with similar antimicrobial and antiprotozoal properties.

Chemistry

Metronidazole benzoate is a salt of benzoic acid and metronidazole. The benzoate component is added to improve the drug's taste, as metronidazole has a bitter taste. The chemical formula of metronidazole benzoate is C13H13N3O4.

Pharmacology

Metronidazole benzoate is a prodrug, which means it is metabolized in the body to its active form, metronidazole. The drug works by inhibiting the growth of anaerobic bacteria and protozoa by interfering with their DNA synthesis.

Clinical uses

Metronidazole benzoate is used to treat a variety of infections, including gastrointestinal infections, skin infections, and respiratory tract infections. It is also used in the treatment of periodontal disease in veterinary medicine.

Side effects

Like all medications, metronidazole benzoate can cause side effects. The most common side effects include nausea, vomiting, and diarrhea. In rare cases, it can cause serious side effects such as seizures, encephalopathy, and peripheral neuropathy.

See also

• Metronidazole
• Benzoic acid
• Prodrug
• Anaerobic bacteria
• Protozoa