MicroRNA 320b-2
MicroRNA 320b-2 (miR-320b-2) is a small non-coding RNA molecule that regulates gene expression. It belongs to the larger class of microRNAs, which are involved in a wide range of biological processes, including development, differentiation, apoptosis, and cancer.
Function[edit | edit source]
miR-320b-2 is involved in the regulation of gene expression. It does this by binding to the mRNA of target genes and preventing their translation into protein. This can have a wide range of effects on cellular processes, depending on the specific genes that are targeted.
Role in Disease[edit | edit source]
Several studies have suggested that miR-320b-2 may play a role in various diseases, including cancer. For example, it has been found to be downregulated in breast cancer and colorectal cancer, suggesting that it may act as a tumor suppressor. In contrast, it has been found to be upregulated in hepatocellular carcinoma, suggesting a potential oncogenic role.
Potential Therapeutic Applications[edit | edit source]
Given its role in disease, miR-320b-2 has been proposed as a potential therapeutic target. For example, restoring its expression in cancer cells could potentially inhibit tumor growth. However, more research is needed to fully understand its function and potential therapeutic applications.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD