Micronucleus
Micronucleus is a small nucleus that forms whenever a chromosome or a fragment of a chromosome is not incorporated into one of the daughter nuclei during cell division. It is an extra nucleus that contains the genetic material left behind from a normal cell division. Micronuclei are a type of nuclear anomaly found in eukaryotic cells.
Formation[edit | edit source]
Micronuclei form during cell division when a chromosome or a fragment of a chromosome fails to incorporate into one of the daughter nuclei. This can occur as a result of chromosome breakage or chromosome mis-segregation. The unincorporated genetic material forms a small, separate nucleus within the cell, known as a micronucleus.
Detection[edit | edit source]
Micronuclei can be detected using various techniques, including fluorescence in situ hybridization (FISH), flow cytometry, and microscopy. These techniques allow for the visualization and quantification of micronuclei in cells.
Clinical significance[edit | edit source]
The presence of micronuclei in cells is often used as a biomarker for genotoxicity and carcinogenesis. Increased levels of micronuclei are associated with a higher risk of cancer and other diseases. Therefore, the detection of micronuclei can be used in the early diagnosis of these diseases.
See also[edit | edit source]
References[edit | edit source]
| Micronucleus Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
