Moclobemide

Moclobemide is a medication that belongs to the class of monoamine oxidase inhibitors (MAOIs). It is primarily used in the treatment of depression and social anxiety.

Etymology

The term "Moclobemide" is derived from the chemical name of the drug, which is morpholinoethyl chlorobenzyloxy aspartate. The name is a combination of parts of this chemical name.

Pharmacology

Moclobemide works by inhibiting the action of a brain enzyme called monoamine oxidase. This enzyme is responsible for breaking down several important neurotransmitters in the brain, including serotonin, norepinephrine, and dopamine. By inhibiting this enzyme, moclobemide increases the levels of these neurotransmitters in the brain, which can help to improve symptoms of depression and anxiety.

Uses

Moclobemide is primarily used to treat depression and social anxiety disorder. It may also be used off-label for other conditions, such as panic disorder and bipolar disorder.

Side Effects

Common side effects of moclobemide include insomnia, nausea, dizziness, and headache. In rare cases, it can cause more serious side effects, such as serotonin syndrome or hypertensive crisis.

Contraindications

Moclobemide should not be used by people with certain medical conditions, such as pheochromocytoma or congestive heart failure. It should also not be used in combination with certain other medications, such as other MAOIs or selective serotonin reuptake inhibitors (SSRIs).

See Also

• Monoamine oxidase inhibitor
• Depression (mood)
• Social anxiety disorder

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