Monofluorophosphate

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Monofluorophosphate is a chemical compound with the formula Na2PO3F. It is commonly used in toothpaste as a source of fluoride, helping to prevent dental caries.

Chemistry[edit | edit source]

Monofluorophosphate, also known as sodium monofluorophosphate, is a salt of the monofluorophosphate ion (PO3F2−) and sodium ion (Na+). It is a white, crystalline, odorless powder that is soluble in water. The monofluorophosphate ion is a derivative of phosphate (PO43−), where one of the oxygen atoms is replaced by a fluorine atom.

Uses[edit | edit source]

The primary use of monofluorophosphate is in toothpaste, where it serves as a source of fluoride. Fluoride is a key ingredient in toothpaste, as it helps to strengthen the tooth enamel and prevent dental caries. Monofluorophosphate is preferred over other sources of fluoride due to its stability and compatibility with other toothpaste ingredients.

Safety[edit | edit source]

Monofluorophosphate is generally considered safe for use in toothpaste. However, excessive ingestion of fluoride can lead to fluorosis, a condition that can cause discoloration and damage to the teeth. Therefore, it is recommended to use only a pea-sized amount of toothpaste when brushing, and to avoid swallowing the toothpaste.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD