Morgan Sheng

Morgan Sheng professor of neuroscience

Morgan Sheng is a prominent neuroscientist known for his significant contributions to the understanding of synaptic biology and neurodegenerative diseases. He has held various academic and research positions and has been influential in the field of neuroscience.

Early Life and Education

Morgan Sheng was born in Hong Kong and later moved to the United Kingdom for his education. He attended Oxford University, where he earned his undergraduate degree in Physiology. Sheng then pursued a Ph.D. in Neurobiology at Harvard University, where he conducted research on synaptic function and plasticity.

Career

After completing his Ph.D., Morgan Sheng joined the faculty at Massachusetts Institute of Technology (MIT) as a professor in the Department of Brain and Cognitive Sciences. During his tenure at MIT, Sheng's research focused on the molecular mechanisms underlying synaptic transmission and plasticity, particularly the role of postsynaptic density proteins.

In 2008, Sheng transitioned to the biotechnology industry, joining Genentech, a leading biotechnology company, where he served as Vice President of Neuroscience. At Genentech, Sheng's work concentrated on developing therapeutic strategies for neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Research Contributions

Morgan Sheng is best known for his research on the molecular composition and function of the postsynaptic density (PSD), a specialized region of the synapse that is crucial for synaptic signaling and plasticity. His work has elucidated the roles of various PSD proteins, including PSD-95, in synaptic function and has provided insights into the molecular basis of learning and memory.

Sheng's research has also explored the mechanisms of synaptic dysfunction in neurodegenerative diseases. His studies have contributed to the understanding of how synaptic proteins are altered in conditions such as Alzheimer's disease, leading to potential therapeutic targets.

Awards and Honors

Throughout his career, Morgan Sheng has received numerous awards and honors for his contributions to neuroscience. These include the National Institutes of Health (NIH) Director's Pioneer Award and election to the American Academy of Arts and Sciences.

Personal Life

Morgan Sheng is married and has two children. He continues to be active in the scientific community, contributing to research and mentoring the next generation of neuroscientists.

Related Pages

• Neuroscience
• Synaptic plasticity
• Neurodegenerative diseases
• Alzheimer's disease
• Parkinson's disease
• Postsynaptic density
• PSD-95
• Massachusetts Institute of Technology
• Genentech