Motretinide
Motretinide is a synthetic derivative of vitamin A, used in the treatment of skin diseases. It is a member of the retinoid family of compounds, which are known for their ability to regulate cell growth and differentiation. Motretinide is primarily used in the treatment of acne and psoriasis, but it has also been investigated for its potential use in the prevention of skin cancer.
History[edit | edit source]
Motretinide was first synthesized in the 1980s by the pharmaceutical company Roche. It was initially developed as a treatment for acne, but its potential use in the treatment of other skin diseases was soon recognized.
Pharmacology[edit | edit source]
Motretinide works by binding to and activating retinoic acid receptors (RARs) in the skin. This leads to an increase in the turnover of skin cells, which can help to clear up acne and reduce the symptoms of psoriasis. In addition, motretinide has been shown to inhibit the growth of skin cancer cells in laboratory studies.
Side Effects[edit | edit source]
The most common side effects of motretinide are skin irritation and increased sensitivity to sunlight. Less common side effects include dry skin, itching, and redness. In rare cases, motretinide can cause severe skin reactions, including erythema multiforme and Stevens-Johnson syndrome.
See Also[edit | edit source]
References[edit | edit source]
Motretinide Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD