Signs and symptoms of multiple sclerosis

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Overview of the signs and symptoms of multiple sclerosis


Symptoms of multiple sclerosis

Multiple sclerosis (MS) is a chronic illness of the central nervous system, characterized by a wide range of neurological symptoms. These symptoms can vary greatly among individuals and can change in severity over time. The symptoms of MS are caused by damage to the myelin sheath, the protective covering that surrounds nerve fibers in the central nervous system.

Common Symptoms[edit | edit source]

Sensory Symptoms[edit | edit source]

Diagram showing the effects of multiple sclerosis on the nervous system

One of the most common initial symptoms of MS is numbness or tingling in the limbs, face, or body. These sensory disturbances are often the result of lesions in the sensory pathways of the spinal cord or brain.

Motor Symptoms[edit | edit source]

MS can lead to muscle weakness, spasticity, and coordination problems. These motor symptoms can affect walking and balance, leading to difficulties in mobility. Tremor and ataxia are also possible, further complicating movement.

Visual Symptoms[edit | edit source]

Internuclear ophthalmoplegia, a condition associated with MS

Visual disturbances are common in MS, with optic neuritis being a frequent initial symptom. This condition involves inflammation of the optic nerve, leading to pain and temporary vision loss. Diplopia (double vision) and nystagmus (involuntary eye movements) can also occur.

Cognitive and Emotional Symptoms[edit | edit source]

Cognitive impairment is a significant concern in MS, affecting memory, attention, and problem-solving abilities. Emotional changes, such as depression and anxiety, are also prevalent, impacting the quality of life.

Fatigue[edit | edit source]

Fatigue is one of the most disabling symptoms of MS, affecting up to 80% of patients. It is characterized by an overwhelming sense of tiredness that is not necessarily related to physical activity and can significantly impact daily functioning.

Less Common Symptoms[edit | edit source]

Speech and Swallowing Difficulties[edit | edit source]

MS can affect the muscles involved in speech and swallowing, leading to dysarthria (slurred speech) and dysphagia (difficulty swallowing).

Bladder and Bowel Dysfunction[edit | edit source]

Bladder dysfunction, such as urgency, frequency, and incontinence, is common in MS. Bowel issues, including constipation and, less frequently, incontinence, can also occur.

Sexual Dysfunction[edit | edit source]

Sexual dysfunction is a common but often underreported symptom of MS, affecting both men and women. It can result from neurological damage, psychological factors, or medication side effects.

Paroxysmal Symptoms[edit | edit source]

Paroxysmal symptoms are sudden, brief episodes of neurological dysfunction. These can include trigeminal neuralgia, Lhermitte's sign, and tonic spasms.

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Contributors: Prab R. Tumpati, MD