Signs and symptoms of multiple sclerosis

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Signs and Symptoms of Multiple Sclerosis

Multiple Sclerosis (MS) is a chronic, potentially debilitating disease that affects the central nervous system, which comprises the brain, spinal cord, and optic nerves. The disease causes the immune system to mistakenly attack the protective sheath (myelin) that covers nerve fibers, leading to communication problems between the brain and the rest of the body. Eventually, the disease can cause permanent damage or deterioration of the nerves. The signs and symptoms of MS can vary widely and depend on the amount of nerve damage and which nerves are affected. Some people with severe MS may lose the ability to walk independently, while others may experience long periods of remission without any new symptoms.

Common Signs and Symptoms[edit | edit source]

The following are some of the most common signs and symptoms of Multiple Sclerosis:

  • Fatigue: Fatigue is one of the most common symptoms, affecting about 80% of people with MS. It can significantly interfere with a person's ability to function at work and at home.
  • Walking Difficulties: MS can cause muscle weakness, spasticity, loss of balance, and coordination problems, making it difficult to walk.
  • Numbness or Weakness: Numbness, weakness, or tingling sensations typically occur on one side of the body at a time, or the legs and trunk.
  • Vision Problems: Acute or chronic visual disturbances, including partial or complete loss of vision, usually in one eye at a time, often with pain during eye movement (optic neuritis), blurred vision, and double vision.
  • Spasticity and Muscle Spasms: Increased muscle tone leading to stiffness and involuntary muscle spasms, particularly in the legs.
  • Dizziness and Vertigo: Feelings of dizziness and vertigo are common and can affect balance and coordination.
  • Bladder and Bowel Problems: Dysfunction of the bladder and bowel is common, including urgency, frequency, incomplete emptying, or constipation.
  • Cognitive Changes: Cognitive changes can include difficulties with memory, attention, processing information, planning, and problem-solving.
  • Emotional Changes and Depression: Emotional instability, mood swings, and depression are common among people with MS.
  • Pain: Chronic pain and abnormal sensations, such as burning, itching, or shooting pain, are frequent in people with MS.

Less Common Symptoms[edit | edit source]

Some less common symptoms include:

  • Speech Disorders: Difficulty in articulating words, known as dysarthria, and changes in speech patterns.
  • Swallowing Problems: Dysphagia, or difficulty swallowing, can occur in more advanced stages of MS.
  • Hearing Loss: Although rare, some individuals may experience hearing loss.
  • Seizures: A small percentage of people with MS may develop seizures.
  • Breathing Problems: Compromised respiratory function can occur in advanced MS.
  • Itching: Unexplained itching without a visible cause can be a symptom of MS.

Diagnosis[edit | edit source]

Diagnosing MS involves a combination of medical history, physical exams, and diagnostic tests, including MRI scans of the brain and spinal cord, spinal tap (lumbar puncture) for cerebrospinal fluid analysis, and evoked potentials tests, which measure electrical activity in the brain in response to stimuli.

Treatment[edit | edit source]

While there is no cure for Multiple Sclerosis, treatments can help manage symptoms and slow the disease's progression. Treatment options include disease-modifying therapies (DMTs), steroids for acute flare-ups, physical therapy, and medications to manage symptoms such as muscle spasms, fatigue, and bladder or bowel control problems.

Living with Multiple Sclerosis[edit | edit source]

Living with MS requires adapting to a new lifestyle and managing the chronic symptoms of the disease. Support from healthcare providers, family, friends, and support groups can help individuals cope with the physical and emotional challenges of MS.

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Contributors: Prab R. Tumpati, MD