Muscarinic

Muscarinic acetylcholine receptors, or mAChRs, are a type of acetylcholine receptor that are more responsive to muscarine than to nicotine. They play several roles in the body including regulation of heart rate, smooth muscle contraction, and neurotransmission in the central nervous system.

Structure

Muscarinic acetylcholine receptors are G protein-coupled receptors (GPCRs) that are linked to an intracellular second messenger cascade. They are composed of five different subtypes, named M1 through M5, each with a distinct pharmacological profile.

Function

Muscarinic receptors are involved in a variety of physiological functions. They regulate heart rate, smooth muscle contraction, and neurotransmission in the central nervous system. They also play a role in learning and memory, as well as in the regulation of the immune system.

Pharmacology

Muscarinic receptors are the target of a number of drugs, including atropine, scopolamine, and various anticholinergics. These drugs can be used to treat a variety of conditions, including Parkinson's disease, chronic obstructive pulmonary disease, and overactive bladder.

See also

• Nicotinic acetylcholine receptor
• G protein-coupled receptor
• Muscarine
• Atropine
• Scopolamine

Muscarinic Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski