25-NB

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(Redirected from NBOMe series)

25-NB[edit | edit source]

General structure of 25-NB compounds

25-NB refers to a class of psychedelic phenethylamines that are derived from the 2C family of compounds. These substances are known for their potent hallucinogenic effects and have been used in both recreational and research settings. The "NB" in the name stands for "N-benzyl," indicating the presence of a benzyl group attached to the nitrogen atom of the phenethylamine backbone.

Structure and Chemistry[edit | edit source]

The general structure of 25-NB compounds includes a phenethylamine core with a methoxy group at the 2 and 5 positions of the benzene ring, and a benzyl group attached to the nitrogen atom. This structure is responsible for the unique pharmacological properties of these compounds.

Variants[edit | edit source]

Several variants of 25-NB compounds exist, each with different substituents on the benzyl group, leading to variations in their effects and potency. Some of the notable variants include:

  • 25B-NB
  • 25C-NB
  • 25I-NB

2C-I-NBOMe[edit | edit source]

Structure of 2C-I-NBOMe

2C-I-NBOMe is one of the most well-known derivatives of the 25-NB series. It is known for its high potency and has been used in both recreational and research contexts.

Pharmacology[edit | edit source]

25-NB compounds act primarily as agonists at the 5-HT2A receptor, which is believed to be responsible for their psychedelic effects. The presence of the N-benzyl group significantly increases the affinity of these compounds for the receptor, making them much more potent than their 2C counterparts.

Effects[edit | edit source]

The effects of 25-NB compounds can vary widely depending on the specific variant and dosage. Common effects include:

  • Visual and auditory hallucinations
  • Altered perception of time and space
  • Enhanced mood and euphoria
  • Increased sensory awareness

Safety and Legal Status[edit | edit source]

Due to their high potency and potential for adverse effects, many 25-NB compounds are classified as controlled substances in various countries. Users should exercise caution and be aware of the legal status of these substances in their region.

Related Pages[edit | edit source]

Gallery[edit | edit source]

  • Structure of 25B-NB

  • Structure of 25C-NB

  • Structure of 25I-NB

  • Structure of 25I-NMeTh

  • Structure of 25B-NMePyr

  • Structure of 25I-NMeFur

  • Structure of 25I-NMeTHF

  • Structure of 25B-NBF

  • Structure of 25B-NBOH

25-NB[edit | edit source]

  • 25-NB

  • 2C-I-NBOMe skeletal structure

  • 25B-NB structure

  • 25C-NB structure

  • 25I-NB structure

  • 25I-NMeTh structure

  • 25B-NMePyr structure

  • 25I-NMeFur structure

  • 25I-NMeTHF structure

  • 25B-NBF

  • 25B-NBOH structure

  • 2C-B-NBOMe skeletal structure

  • 25-NB

  • 2C-I-NBOMe

  • 25B-NB

  • 25C-NB

  • 25I-NB

  • 25I-NMeTh

  • 25B-NMePyr

  • 25I-NMeFur

  • 25I-NMeTHF

  • 25B-NBF

  • 25B-NBOH

  • 2C-B-NBOMe

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Contributors: Prab R. Tumpati, MD