25-NB

25-NB is a series of substituted phenethylamine derivatives, which are known for their psychedelic and hallucinogenic effects. These compounds are part of a larger family of psychedelic phenethylamines, which also includes substances like 2C-B, 2C-I, and mescaline. The 25-NB series was first synthesized and studied by the chemist Alexander Shulgin in his book PiHKAL.

Chemistry

The 25-NB compounds are phenethylamine derivatives, which means they are made by substituting different groups on the phenethylamine molecule. The name "25-NB" comes from the fact that the substitutions are made at the 2 and 5 positions of the molecule. The "NB" stands for "N-Benzyl", which refers to the benzyl group that is attached to the nitrogen atom of the phenethylamine molecule.

Pharmacology

The 25-NB compounds are believed to work by acting as agonists at the 5-HT2A receptor, which is the same receptor that many other psychedelic drugs act on. This receptor is involved in the regulation of mood, anxiety, and perception, which explains the psychedelic effects of these drugs.

Effects

The effects of the 25-NB compounds can vary greatly depending on the specific compound and the dose taken. However, common effects reported by users include visual hallucinations, altered perception of time, enhanced introspection, and euphoria. Some users also report negative effects such as anxiety, paranoia, and uncomfortable physical sensations.

Legal Status

The legal status of the 25-NB compounds varies by country. In many countries, including the United States, these compounds are classified as Schedule I drugs, which means they are illegal to manufacture, distribute, or possess.

See Also

• Phenethylamine
• Psychedelic drug
• Hallucinogen
• Alexander Shulgin
• PiHKAL