NFIC (gene)
NFIC (Nuclear Factor I C) is a gene that encodes a protein in humans. It is also known as CTF, CTF1, NF-I/C, and NFI-C. The NFIC gene is located on the short (p) arm of chromosome 19 at position 13.3.
Function[edit | edit source]
The NFIC gene provides instructions for making a protein that is part of a family of proteins known as nuclear factor I (NFI). These proteins bind to DNA and control the activity of other genes. The NFIC protein is involved in the development and function of the tooth and bone.
Clinical significance[edit | edit source]
Mutations in the NFIC gene have been associated with tooth agenesis, a condition characterized by the absence of one or more teeth. These mutations can affect the function of the NFIC protein, leading to abnormal tooth development.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- NFIC gene on the US National Library of Medicine website
- NFIC gene on the Genetics Home Reference website
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