NOSH-aspirin

NOSH-aspirin (also known as Nitric Oxide and Hydrogen Sulfide-releasing Aspirin) is a novel aspirin derivative that has been developed to overcome the gastrointestinal side effects associated with traditional aspirin use. It is a nonsteroidal anti-inflammatory drug (NSAID) that releases both nitric oxide (NO) and hydrogen sulfide (H2S).

Mechanism of Action

NOSH-aspirin works by releasing nitric oxide and hydrogen sulfide. These two gases have been shown to have various beneficial effects in the body. Nitric oxide is a potent vasodilator and has anti-platelet properties, while hydrogen sulfide has been shown to have anti-inflammatory and gastro-protective properties.

Development and Research

NOSH-aspirin was developed by researchers at the City University of New York (CUNY). In preclinical studies, it has been shown to be more effective than traditional aspirin in reducing inflammation and preventing the formation of colorectal cancer cells. However, as of 2021, it is still in the experimental stage and has not yet been approved for use in humans.

Potential Benefits

The main potential benefit of NOSH-aspirin is its ability to provide the anti-inflammatory and anti-platelet benefits of aspirin, without the associated risk of gastrointestinal side effects. This could make it a valuable tool in the prevention of conditions such as heart disease and colorectal cancer.

See Also

• Aspirin
• Nonsteroidal anti-inflammatory drug
• Nitric oxide
• Hydrogen sulfide

References

NOSH-aspirin Resources
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