Nanobiotix

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Nanobiotix is a leading company in the field of nanotechnology applied to medicine, specifically focusing on the development of novel nanoparticle therapies for the treatment of cancer. The company's innovative approach combines the physical properties of nanoparticles with traditional cancer treatments to enhance their efficacy and reduce side effects. Nanobiotix's flagship product, NBTXR3, is a first-in-class radio-enhancer nanoparticle designed to increase the effectiveness of radiotherapy in various types of cancer.

Overview[edit | edit source]

Nanobiotix was founded with the goal of leveraging nanotechnology to create better therapeutic options for cancer patients. The company's research and development efforts are centered around nanoparticles that can be activated by external stimuli, such as radiation, to induce tumor cell death without harming surrounding healthy tissues. This technology represents a significant advancement in oncology, offering the potential for more targeted and effective cancer treatments.

NBTXR3[edit | edit source]

NBTXR3, Nanobiotix's leading product, is composed of hafnium oxide nanoparticles. When injected directly into a tumor and exposed to radiation, NBTXR3 nanoparticles absorb the radiation and emit higher energy levels within the tumor. This process enhances the local destruction of cancer cells while minimizing damage to adjacent healthy cells. NBTXR3 has shown promise in clinical trials for treating various cancers, including soft tissue sarcoma, head and neck cancer, and liver cancer.

Clinical Trials[edit | edit source]

Nanobiotix has conducted several clinical trials to evaluate the safety and efficacy of NBTXR3. These trials have demonstrated that NBTXR3, in combination with radiotherapy, can significantly improve treatment outcomes in cancer patients. The company continues to explore the potential of NBTXR3 in other cancer types and in combination with other therapeutic modalities, such as immunotherapy.

Future Directions[edit | edit source]

The success of NBTXR3 has positioned Nanobiotix as a pioneer in the field of nanomedicine for cancer treatment. The company is committed to furthering the development of its nanoparticle technology to address a wider range of cancers and to explore its potential in other medical applications beyond oncology. With ongoing research and development, Nanobiotix aims to revolutionize cancer treatment and improve the quality of life for patients worldwide.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD