Nanobiotix

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Nanobiotix[edit | edit source]

Nanobiotix logo

Nanobiotix is a nanomedicine company that focuses on the development of nanoparticles for cancer treatment. The company is known for its innovative approach to enhancing the efficacy of radiotherapy using its proprietary technology.

History[edit | edit source]

Nanobiotix was founded in 2003 and is headquartered in Paris, France. The company was established with the aim of leveraging nanotechnology to improve cancer treatment outcomes. Over the years, Nanobiotix has developed a range of products that utilize nanoparticles to enhance the effects of traditional cancer therapies.

Technology[edit | edit source]

The core technology of Nanobiotix involves the use of nanoparticles to increase the effectiveness of radiotherapy. These nanoparticles are designed to accumulate in tumor tissues and amplify the radiation dose received by the cancer cells, thereby increasing the likelihood of destroying the tumor while minimizing damage to surrounding healthy tissues.

Nanoparticles in Radiotherapy[edit | edit source]

Nanobiotix's nanoparticles are engineered to interact with X-rays used in radiotherapy. When these nanoparticles are exposed to radiation, they produce secondary electrons that cause additional damage to the cancer cells. This process enhances the therapeutic index of radiotherapy, potentially allowing for lower doses of radiation to achieve the same or better therapeutic outcomes.

Products[edit | edit source]

Nanobiotix has developed several products based on its nanoparticle technology. The most notable product is NBTXR3, which is designed to be injected directly into tumors. NBTXR3 is currently being evaluated in clinical trials for various types of cancer, including head and neck cancer, liver cancer, and prostate cancer.

Clinical Trials[edit | edit source]

Nanobiotix is actively involved in clinical trials to assess the safety and efficacy of its products. These trials are conducted in collaboration with leading cancer research centers and hospitals around the world. The results of these trials will determine the future applications of Nanobiotix's technology in cancer treatment.

Future Directions[edit | edit source]

The future of Nanobiotix lies in expanding the applications of its nanoparticle technology beyond radiotherapy. The company is exploring the potential of its technology in combination with other cancer treatments, such as immunotherapy and chemotherapy.

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Contributors: Prab R. Tumpati, MD