Nantenine

Nantenine is an alkaloid that is found in the plant Nandina domestica (also known as heavenly bamboo or sacred bamboo). It is a competitive antagonist at the 5-HT2A receptor, 5-HT2B receptor, and 5-HT2C receptor. Nantenine has been found to act as an antagonist at the alpha-1 adrenergic receptor, alpha-2 adrenergic receptor, and 5-HT1A receptor as well.

Chemistry

Nantenine is a member of the class of compounds known as aporphines. Aporphines are organic compounds containing the aporphine skeleton, which is a tetracyclic aromatic compound derived from benzylisoquinoline.

Pharmacology

Nantenine has been found to act as an antagonist at the 5-HT2A receptor, 5-HT2B receptor, and 5-HT2C receptor. It has also been found to act as an antagonist at the alpha-1 adrenergic receptor, alpha-2 adrenergic receptor, and 5-HT1A receptor.

Toxicity

The toxicity of nantenine is not well-studied. However, it is known that the plant Nandina domestica, which contains nantenine, is toxic to some animals, including cats and birds.

See also

• Nandina domestica
• 5-HT2A receptor
• 5-HT2B receptor
• 5-HT2C receptor
• alpha-1 adrenergic receptor
• alpha-2 adrenergic receptor
• 5-HT1A receptor

Nantenine Resources
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