Nemolizumab
| Nemolizumab | |
|---|---|
| [[File:|frameless|220px|alt=|]] | |
| INN | |
| Drug class | |
| Routes of administration | Subcutaneous injection |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | Proteolytic enzymes |
| Elimination half-life | |
| Excretion | |
| Legal status | Investigational |
| CAS Number | 1476039-58-3 |
| PubChem | |
| DrugBank | |
| ChemSpider | none |
| KEGG | D11080 |
Nemolizumab is an experimental drug for the treatment of itching in people with atopic dermatitis.[1] It is a monoclonal antibody that blocks the interleukin-31 receptor A.[2] Results of a Phase II clinical trial were published in March 2017.[3]
Nemolizumab was invented by Chugai, who sold an exclusive license for the drug's development and worldwide marketing (except Japan and Taiwan) to Galderma in 2016.[4]
References[edit | edit source]
- ↑ H. Spreitzer, Neue Wirkstoffe - Nemolizumab, Österreichische Apothekerzeitung, (Issue: 7/2017),
- ↑ , International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended INN: List 74, WHO Drug Information, 2015, Vol. 29(Issue: 3), Full text,
- ↑ , Anti-Interleukin-31 Receptor A Antibody for Atopic Dermatitis, New England Journal of Medicine, 2017, Vol. 376(Issue: 9), pp. 826–835, DOI: 10.1056/NEJMoa1606490, PMID: 28249150,
- ↑ , Chugai grants exclusive global license for development and marketing of nemolizumab to Galderma Full text, , Pharmabiz.com, 22 July 2016,
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