Mepyramine

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Mepyramine also known as pyrilamine, is a first generation H1 receptor antagonist that is used in the treatment of allergic reactions, hay fever, and rhinitis. It is a member of the ethylenediamine class of antihistamines and is also classified as an anticholinergic.

Etymology[edit | edit source]

The term "mepyramine" is derived from the chemical structure of the compound, which includes a pyrimidine ring. The prefix "me-" is short for "methyl", referring to the methyl group attached to the pyrimidine ring.

Pharmacology[edit | edit source]

Mepyramine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. It does this by binding to the H1 receptor, preventing histamine from binding and causing symptoms. This makes it effective in relieving symptoms such as sneezing, itching, watery eyes, and runny nose.

Uses[edit | edit source]

Mepyramine is used to treat a variety of allergic conditions, including hay fever and rhinitis. It can also be used to relieve itching caused by hives and other skin conditions. In addition, it is sometimes used in combination with other medications to treat severe allergic reactions.

Side Effects[edit | edit source]

Like all medications, mepyramine can cause side effects. These may include drowsiness, dizziness, blurred vision, upset stomach, constipation, dry mouth/nose/throat, or trouble sleeping. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Related Terms[edit | edit source]

See Also[edit | edit source]

Mepyramine Resources
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Contributors: Prab R. Tumpati, MD