Netarsudil/latanoprost

Netarsudil/Latanoprost is a combination drug used for the treatment of glaucoma and ocular hypertension. It is a combination of two active ingredients, Netarsudil and Latanoprost, which work together to reduce intraocular pressure.

Etymology

The name "Netarsudil" is derived from the chemical name "N-ethyltartrate-sudil". "Latanoprost" is derived from the Latin words "lata" meaning wide and "prost" meaning first, referring to its use as a first-line treatment for wide-angle glaucoma.

Pharmacology

Netarsudil is a Rho kinase inhibitor and norepinephrine transporter inhibitor. It works by increasing the outflow of aqueous humor, the fluid in the eye, thereby reducing intraocular pressure. Latanoprost is a prostaglandin analogue. It works by increasing the outflow of aqueous humor through the uveoscleral pathway, an alternative pathway for fluid to exit the eye.

Indications

Netarsudil/Latanoprost is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Side Effects

The most common side effects of Netarsudil/Latanoprost include conjunctival hyperemia, corneal verticillata, instillation site pain, and conjunctival hemorrhage.

Related Terms

• Glaucoma
• Ocular hypertension
• Intraocular pressure
• Aqueous humor
• Rho kinase inhibitor
• Norepinephrine transporter inhibitor
• Prostaglandin analogue
• Uveoscleral pathway
• Conjunctival hyperemia
• Corneal verticillata
• Instillation site pain
• Conjunctival hemorrhage