Netarsudil/latanoprost

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Netarsudil/Latanoprost is a combination drug used for the treatment of glaucoma and ocular hypertension. It is a combination of two active ingredients, Netarsudil and Latanoprost, which work together to reduce intraocular pressure.

Etymology[edit | edit source]

The name "Netarsudil" is derived from the chemical name "N-ethyltartrate-sudil". "Latanoprost" is derived from the Latin words "lata" meaning wide and "prost" meaning first, referring to its use as a first-line treatment for wide-angle glaucoma.

Pharmacology[edit | edit source]

Netarsudil is a Rho kinase inhibitor and norepinephrine transporter inhibitor. It works by increasing the outflow of aqueous humor, the fluid in the eye, thereby reducing intraocular pressure. Latanoprost is a prostaglandin analogue. It works by increasing the outflow of aqueous humor through the uveoscleral pathway, an alternative pathway for fluid to exit the eye.

Indications[edit | edit source]

Netarsudil/Latanoprost is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Side Effects[edit | edit source]

The most common side effects of Netarsudil/Latanoprost include conjunctival hyperemia, corneal verticillata, instillation site pain, and conjunctival hemorrhage.

Related Terms[edit | edit source]

Netarsudil/latanoprost Resources
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Contributors: Prab R. Tumpati, MD