Etafedrine

Etafedrine

Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has the brand name Nethaprin. It is similar in structure to ephedrine, and acts as a sympathomimetic.

Pharmacology

Etafedrine is a bronchodilator and a vasodilator that is used to relieve bronchial spasms. It is a sympathomimetic drug that acts on the adrenergic receptor system, particularly the beta-2 adrenergic receptor, which is responsible for smooth muscle relaxation in the bronchial tubes and vasculature.

Chemistry

Etafedrine is a phenethylamine derivative, and is structurally similar to ephedrine. It is a chiral compound, and is used in medicine as a racemate, an equal mixture of the two enantiomers.

Medical uses

Etafedrine is used in the treatment of asthma and other conditions involving bronchospasm. It is not commonly used, but is considered a second-line treatment when other bronchodilators such as salbutamol (albuterol) are not effective.

Side effects

Like other sympathomimetic drugs, etafedrine can cause side effects such as tachycardia, hypertension, and palpitations. It can also cause nervousness, insomnia, and tremors.

See also

• Ephedrine
• Phenethylamine
• Sympathomimetic drug
• Bronchodilator
• Vasodilator