Non-healing wounds

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Non-healing wounds
Other namesChronic wounds, Non-healing ulcers
SpecialtyDermatology, Surgery
SymptomsPersistent open wound, Delayed healing
ComplicationsInfection, Gangrene, Amputation
CausesDiabetes, Peripheral artery disease, Venous insufficiency, Pressure ulcers
Diagnostic methodClinical examination, Wound culture, Biopsy
TreatmentWound debridement, Dressings, Topical medications, Hyperbaric oxygen therapy, Surgery
PrognosisVariable, depends on underlying cause and patient's overall health
FrequencyCommon



Non-healing wounds, also known as chronic wounds or non-healing ulcers, refer to persistent open wounds that do not heal within the expected timeframe. These wounds can be a significant burden for patients, leading to pain, decreased quality of life, and potential complications such as infection, gangrene, and even amputation.

Causes[edit | edit source]

Non-healing wounds can have various underlying causes, including:

Diabetes: High blood sugar levels in individuals with diabetes can impair blood flow and damage nerves, leading to poor wound healing.

Peripheral artery disease: Narrowing or blockage of the arteries that supply blood to the extremities can result in reduced blood flow to the wound site, hindering the healing process.

Venous insufficiency: Inadequate functioning of the veins, often seen in conditions such as varicose veins, can cause blood to pool in the lower extremities, leading to ulcers that are slow to heal.

Pressure ulcers: Prolonged pressure on specific areas of the body, commonly seen in individuals who are bedridden or use wheelchairs, can result in the development of pressure ulcers that are difficult to heal.

Diagnosis[edit | edit source]

The diagnosis of non-healing wounds involves a comprehensive evaluation by a healthcare professional. This typically includes:

Clinical examination: The healthcare provider will assess the wound's characteristics, such as size, depth, presence of infection, and surrounding tissue condition.

Wound culture: A sample of the wound may be collected and sent to a laboratory for analysis to identify any bacterial or fungal infections that may be impeding the healing process.

Biopsy: In some cases, a small tissue sample may be taken from the wound site to determine the underlying cause of the non-healing wound.

Treatment[edit | edit source]

The treatment of non-healing wounds aims to address the underlying cause, promote wound healing, and prevent complications. The specific treatment approach may vary depending on the individual patient and the characteristics of the wound. Common treatment modalities include:

Wound debridement: Removal of dead or infected tissue from the wound to promote healing and prevent infection.

Dressings: Application of appropriate wound dressings, such as hydrogels, foams, or alginate dressings, to maintain a moist wound environment and facilitate healing.

Topical medications: The use of topical antimicrobial agents or growth factors may be considered to promote wound healing and prevent infection.

Hyperbaric oxygen therapy: In some cases, exposing the wound to high levels of oxygen in a hyperbaric chamber can enhance healing by increasing oxygen delivery to the tissues.

Surgery: Surgical interventions, such as skin grafts or flap procedures, may be necessary for larger or more complex non-healing wounds.

Prognosis[edit | edit source]

The prognosis for non-healing wounds can vary depending on the underlying cause and the patient's overall health. With appropriate treatment and management of the underlying condition, many non-healing wounds can eventually heal. However, some wounds may persist or recur despite treatment, requiring ongoing care and monitoring.

Prevention[edit | edit source]

Prevention plays a crucial role in reducing the risk of non-healing wounds. Some preventive measures include:

- Maintaining good blood sugar control in individuals with diabetes. - Regular exercise and maintaining a healthy weight to improve circulation. - Frequent repositioning and proper cushioning for individuals at risk of pressure ulcers. - Wearing compression stockings or using other appropriate measures to manage venous insufficiency.

See also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD