Nonivamide
Nonivamide, also known as pelargonic acid vanillylamide or PAVA, is an organic compound and a capsaicinoid. It is an amide of vanillyl and pelargonic acid. It is present in chili peppers, but is commonly manufactured synthetically. It is more heat-stable than capsaicin.
Chemistry[edit | edit source]
Nonivamide is a capsaicinoid, a class of compounds that share a similar molecular structure with capsaicin, the active component in chili peppers. Like capsaicin, nonivamide is an irritant, and it produces a sensation of heat in the mouth and on the skin.
Uses[edit | edit source]
Nonivamide is used as a food additive to add pungency to seasonings, flavorings, and spice blends. It is also used in the pharmaceutical industry in some topical medications as an analgesic to relieve minor aches and pains of muscles and joints.
In law enforcement, nonivamide is used as the active ingredient in certain types of pepper spray. When used in this capacity, it is often referred to as PAVA spray. Nonivamide is considered to be a less-toxic alternative to other types of pepper spray.
Safety[edit | edit source]
Nonivamide is generally considered safe for consumption and topical use. However, it can cause skin and eye irritation, especially in high concentrations. Ingestion can cause a burning sensation in the mouth, abdominal pain, and nausea.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD