NovoBiotic Pharmaceuticals
NovoBiotic Pharmaceuticals is a pharmaceutical company that specializes in the discovery and development of new antibiotics from uncultured bacteria. The company was founded in 2003 and is based in Cambridge, Massachusetts, United States.
History[edit | edit source]
NovoBiotic Pharmaceuticals was founded by Kim Lewis and Slava Epstein, two Northeastern University professors who developed a method for growing previously unculturable bacteria in their natural environment. This method, known as the iChip technology, has led to the discovery of several new antibiotics, including Teixobactin.
iChip Technology[edit | edit source]
The iChip, or isolation chip, is a device that allows for the growth of uncultured bacteria in their natural environment. The iChip isolates and grows individual bacterial cells in tiny chambers, each containing a sample of the bacteria's natural environment. This technology has allowed NovoBiotic to discover several new antibiotics, including Teixobactin, which has shown promise in treating drug-resistant infections.
Teixobactin[edit | edit source]
Teixobactin is a new antibiotic discovered by NovoBiotic Pharmaceuticals in 2015. It is the first of a new class of antibiotics that kills bacteria by binding to lipid II and lipid III, essential precursors for bacterial cell wall synthesis. Teixobactin has shown promise in treating drug-resistant infections, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE).
Research and Development[edit | edit source]
NovoBiotic Pharmaceuticals continues to use its iChip technology to discover new antibiotics. The company's research and development efforts are focused on finding treatments for drug-resistant infections, which are a growing global health concern.
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References[edit | edit source]
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