Nuchal scan
The nuchal scan, also known as the nuchal translucency (NT) scan, is a non-invasive prenatal ultrasound screening used to identify potential chromosomal abnormalities in a fetus. The scan measures the clear space, or nuchal translucency, in the tissue at the back of the developing fetus's neck. Abnormalities can result in an increase in this space due to altered extracellular matrix composition and limited lymphatic drainage[1].
Screening Indications[edit | edit source]
While not a diagnostic tool, the nuchal scan is an important part of prenatal screening for conditions such as Down syndrome, Patau syndrome, Edwards syndrome, and non-genetic conditions like body-stalk anomaly. These conditions often involve impaired cardiovascular development, which can manifest as an increased nuchal translucency[2].
Procedure[edit | edit source]
The nuchal scan is typically performed between the 11th and 14th weeks of pregnancy, during the first trimester. The ultrasound technician will measure the nuchal translucency using an ultrasound machine. The procedure is non-invasive and painless for both the mother and the fetus[3].
Interpretation[edit | edit source]
The results of a nuchal scan are usually combined with the results of specific blood tests and the mother's age to calculate the risk of the fetus having a chromosomal abnormality. A larger nuchal translucency measurement can indicate a higher risk of a chromosomal abnormality. However, a definitive diagnosis requires more invasive procedures like amniocentesis or chorionic villus sampling[4].
Risks and Limitations[edit | edit source]
Although the nuchal scan is generally safe, it does have limitations. It cannot provide a definitive diagnosis and there is a chance of false-positive and false-negative results. Additionally, not all chromosomal abnormalities or birth defects can be detected by the nuchal scan[5].
Conclusion[edit | edit source]
Despite these limitations, the nuchal scan remains an important tool in prenatal screening, providing early identification of potential chromosomal abnormalities. It allows healthcare providers and parents to make informed decisions about further testing and management of the pregnancy.
References[edit | edit source]
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