Nucleoporin 37

Nucleoporin 37 (Nup37) is a protein that in humans is encoded by the NUP37 gene. It is a component of the nuclear pore complex, a structure that regulates the movement of molecules between the nucleus and the cytoplasm.

Function

Nucleoporin 37 is one of the many nucleoporins that make up the nuclear pore complex. This complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells.

Clinical significance

Mutations in the NUP37 gene have been associated with various diseases, including cancer. Further research is needed to fully understand the role of NUP37 in disease development and progression.

See also

• Nuclear pore
• Nucleoporin
• NUP107
• NUP160