O-Desmethylangolensin

O-Desmethylangolensin (also known as ODMA) is a metabolite produced by the microbiota in the human gut. It is a derivative of the isoflavone daidzein, which is found in soy and other legumes. O-Desmethylangolensin is produced by the action of enzymes produced by certain bacteria in the gut.

Metabolism

O-Desmethylangolensin is produced from daidzein by the action of the enzyme beta-glucuronidase, which is produced by certain bacteria in the gut. This process is known as deconjugation. The resulting metabolite is then further metabolized by other enzymes to produce O-Desmethylangolensin.

Health Effects

O-Desmethylangolensin has been studied for its potential health effects. Some studies have suggested that it may have estrogenic effects, which could potentially influence the risk of certain diseases, such as breast cancer. However, the evidence is not conclusive, and more research is needed to fully understand the health effects of O-Desmethylangolensin.

See Also

• Isoflavone
• Daidzein
• Microbiota
• Metabolite

References

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