OR10G8

OR10G8 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 10 Subfamily G Member 8. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors are G protein-coupled receptors that play a role in the detection of smell.

Function

The OR10G8 gene is a member of the olfactory receptor genes family. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.

Expression

OR10G8 is expressed in the olfactory epithelium, where it is involved in the detection of odorants. The specific function of this protein has not yet been determined; however, it may play a role in the perception of odorants in the olfactory epithelium.

Clinical Significance

While the specific clinical significance of OR10G8 is not yet fully understood, mutations in olfactory receptor genes, including OR10G8, have been associated with various diseases. For example, a decreased sense of smell (anosmia) can be caused by mutations in olfactory receptor genes.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia