OR10K1
OR10K1 is a gene that encodes a protein in the olfactory receptor family. The olfactory receptors olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.
Function[edit | edit source]
The OR10K1 gene is part of the olfactory receptor family, a class of proteins that are responsible for detecting odors and transmitting signals to the brain. These proteins are located in the cell membranes of olfactory receptor neurons in the nose and are activated by odorant molecules.
Structure[edit | edit source]
The OR10K1 gene is located on chromosome 1, specifically at 1q44. It spans approximately 1.1 kilobases and consists of a single coding exon. The protein encoded by this gene is a member of the G-protein coupled receptor 1 family, which are proteins that contain seven transmembrane domains and are involved in G-protein signaling.
Clinical Significance[edit | edit source]
While the specific role of OR10K1 in human health and disease is not yet fully understood, olfactory receptors in general have been implicated in a variety of diseases and conditions. For example, alterations in olfactory receptor function can lead to anosmia, the inability to perceive odor, or hyperosmia, an increased sensitivity to odors.
Research[edit | edit source]
Research into the OR10K1 gene and its associated protein is ongoing. Understanding the specific role and function of this gene could provide insights into the complex process of olfaction and potentially lead to new treatments for olfactory disorders.
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