OR11H7

OR11H7 is a gene that encodes a protein in the olfactory receptor family. This family is responsible for the detection of odor molecules, and the encoded protein is thought to play a role in the perception of smell.

Function

The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Clinical significance

While the specific function of OR11H7 in humans is not well understood, mutations in this gene have been associated with changes in smell perception. These changes can range from a complete loss of smell, known as anosmia, to a reduced ability to smell, known as hyposmia.

See also

• Olfactory receptor
• Anosmia
• Hyposmia

External links

• GeneNames.org: OR11H7
• NCBI Gene: OR11H7

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