OR1F2

From WikiMD's Food, Medicine & Wellness Encyclopedia

OR1F2 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 1 Subfamily F Member 2. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.

Function[edit | edit source]

The OR1F2 gene provides instructions for making a protein that is involved in the detection of smell (olfaction). This protein is a member of the olfactory receptor family of proteins. These proteins are part of the G protein-coupled receptor superfamily, which play a role in transmitting signals from outside the cell into the cell through a process called signal transduction.

Clinical significance[edit | edit source]

Mutations in the OR1F2 gene have been associated with a reduced ability to smell (anosmia). However, the clinical significance of this gene is not fully understood and further research is needed.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD