OR1K1

OR1K1 is a gene that encodes the olfactory receptor, family 1, subfamily K, member 1. It is a protein that is part of the olfactory receptor family, which is involved in the detection of smell. The OR1K1 gene is located on chromosome 1, specifically at 1q44.

Function

The OR1K1 gene is part of the olfactory receptor gene family, which is the largest gene family in the genome. The family members are G-protein coupled receptors that respond to smell. This receptor is localized in the cilia of olfactory sensory neurons.

Structure

The OR1K1 protein is a member of the G protein-coupled receptor superfamily. This particular receptor is known for its olfactory-specific expression pattern. The protein is approximately 312 amino acids in length, with a molecular weight of approximately 35 kDa.

Clinical Significance

Alterations in the OR1K1 gene have been associated with a variety of conditions, including anosmia, which is the inability to perceive smell. Further research is needed to fully understand the clinical significance of this gene.

Research

Research on the OR1K1 gene is ongoing, with studies focusing on its role in olfaction and potential links to disease. The gene is of interest due to its role in the olfactory system, which is critical for smell perception.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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