OR1N2

OR1N2 is a gene that encodes a member of the olfactory receptor family of proteins. These receptors are responsible for the detection of odor molecules and are a part of the G protein-coupled receptor (GPCR) superfamily.

Function

Olfactory receptors, such as OR1N2, interact with odorant molecules in the olfactory epithelium to initiate a neuronal response that results in the perception of a smell. The olfactory receptor proteins are characterized by a 7-transmembrane domain structure, which is a common feature of many neurotransmitter and hormone receptors.

The OR1N2 gene is one of the many olfactory receptor genes located on chromosome 9. These genes are responsible for the recognition and G protein-mediated transduction of odorant signals.

Gene Family

The olfactory receptor gene family is the largest in the human genome. The nomenclature for these genes and proteins is independent of other organisms.

Clinical Significance

While the primary function of OR1N2 is related to the sense of smell, variations in olfactory receptor genes can influence individual differences in odor perception. However, specific clinical conditions directly associated with OR1N2 have not been extensively documented.

Research

Research into olfactory receptors like OR1N2 continues to provide insights into the mechanisms of smell and the potential for olfactory receptors to be involved in other physiological processes.

See Also

• Olfactory system
• G protein-coupled receptor
• Chromosome 9 (human)

External Links

• OR1N2 Gene - NCBI
• OR1N2 Gene - GeneCards