OR1Q1
OR1Q1 is a gene that encodes the olfactory receptor, family 1, subfamily Q, member 1 in humans. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.
Function[edit | edit source]
The OR1Q1 gene is part of the olfactory receptor gene family, which is the largest gene family in the human genome. The proteins encoded by these genes function in the detection of odorants, and are expressed in the olfactory epithelium of the nose.
Structure[edit | edit source]
The OR1Q1 gene is located on chromosome 17q25.3 and is composed of 1 exon encoding a protein of 312 amino acids. The protein structure is characterized by seven transmembrane domains, a characteristic of the large family of G protein-coupled receptors (GPCRs).
Clinical Significance[edit | edit source]
While the specific clinical significance of OR1Q1 is not yet fully understood, the olfactory receptor family as a whole is of significant interest in biomedical research. Alterations in our sense of smell can be an early indicator for a number of health conditions including neurodegenerative diseases like Parkinson's disease and Alzheimer's disease.
Research[edit | edit source]
Research into the function and potential clinical significance of OR1Q1 is ongoing. Understanding the role of individual olfactory receptors like OR1Q1 may provide insights into how our sense of smell works and how it is connected to other physiological processes.
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