OR2A12
OR2A12 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors that are involved in the detection of smell. The OR2A12 gene is specifically expressed in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell.
Function[edit | edit source]
The OR2A12 gene encodes a member of the olfactory receptor family of proteins. These proteins are a type of G protein-coupled receptor that are activated by small molecules in the air, leading to the perception of smell. The specific function of the OR2A12 protein is not well understood, but it is thought to be involved in the detection of specific odors.
Structure[edit | edit source]
The OR2A12 protein is a member of the G protein-coupled receptor family, which are characterized by seven transmembrane domains. These domains form a pocket in the cell membrane where small molecules can bind, leading to a change in the shape of the protein and the activation of a signal transduction pathway.
Clinical significance[edit | edit source]
Mutations in the OR2A12 gene have been associated with a reduced ability to smell, a condition known as anosmia. However, the specific role of the OR2A12 gene in this condition is not well understood.
See also[edit | edit source]
References[edit | edit source]
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