OR2C1

OR2C1 is a gene that encodes the olfactory receptor 2C1 in humans. The olfactory receptor family is believed to be the largest gene family in the human genome. These receptors are responsible for the detection of odor molecules, playing a crucial role in the sense of smell.

Function

The OR2C1 gene is part of the olfactory receptor family, a class of G protein-coupled receptors (GPCRs) which are located in the olfactory epithelium in the nose. These receptors are activated by odor molecules in the air, leading to the perception of smell. Each olfactory receptor gene, including OR2C1, is expressed in a unique small subset of olfactory receptor neurons.

Structure

Like all olfactory receptors, the protein encoded by the OR2C1 gene has seven transmembrane domains, making it a member of the G protein-coupled receptor family. This structure allows it to receive a signal from an odor molecule and transmit that signal to the inside of the neuron.

Clinical Significance

While the primary role of olfactory receptors is in the perception of smell, there is increasing evidence that these receptors may also play other roles in the body. For example, some olfactory receptors are expressed in other tissues, such as the lung and testis, and may play roles in various diseases or conditions. However, the specific role of OR2C1 in disease is not yet well understood.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Olfactory epithelium

References

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