OR2S2

OR2S2 is a gene that encodes a member of the olfactory receptor family of proteins. These receptors are involved in the detection of odor molecules and are a part of the G-protein-coupled receptor (GPCR) superfamily.

Function

Olfactory receptors, such as those encoded by the OR2S2 gene, are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor proteins are characterized by a 7-transmembrane domain structure, which is also shared by many neurotransmitter and hormone receptors.

Gene Family

The olfactory receptor gene family is the largest in the human genome. The OR2S2 gene is one of many that contribute to the diversity of olfactory receptors, allowing humans to detect a wide range of smells.

Location

The OR2S2 gene is located on the long arm (q) of chromosome 1, specifically at band 44.2. This location is part of a cluster of olfactory receptor genes.

Clinical Significance

While the primary function of OR2S2 is related to olfaction, variations in olfactory receptor genes can sometimes be associated with differences in smell perception among individuals. However, specific clinical conditions directly linked to OR2S2 have not been extensively documented.

Research

Research into olfactory receptors like OR2S2 continues to explore their role in the sensory system and potential implications in other physiological processes. Understanding these receptors can provide insights into the mechanisms of smell and its impact on behavior and health.

See Also

• Olfactory receptor
• G-protein-coupled receptor
• Chromosome 1

External Links

• NCBI Gene: OR2S2
• GeneCards: OR2S2