OR3A2
OR3A2 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are responsible for detecting molecules in the environment and subsequently initiating a neuronal response. The olfactory receptor proteins interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.
Function[edit | edit source]
The olfactory receptor family is the largest in the genome. The family members of OR3A2 are located in a cluster of similar genes and pseudogenes on chromosome 17. This particular gene, OR3A2, is thought to have a role in the detection of specific odorants.
Structure[edit | edit source]
The OR3A2 gene is located on chromosome 17 and is part of a cluster of similar genes and pseudogenes. The gene encodes a protein that is a member of the olfactory receptor family. This protein is a G protein-coupled receptor that is responsible for detecting molecules in the environment and initiating a neuronal response.
Clinical Significance[edit | edit source]
While the specific clinical significance of OR3A2 is not fully understood, it is known that mutations in olfactory receptor genes can lead to a reduced ability to smell, a condition known as anosmia. Further research is needed to understand the specific role of OR3A2 in human health and disease.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD