OR3A4

From WikiMD's Wellness Encyclopedia

OR3A4 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors that are involved in the detection of smell. The OR3A4 protein is specifically involved in the detection of certain odors.

Function[edit | edit source]

The OR3A4 gene is part of the olfactory receptor family, which is responsible for the detection of odors. These receptors are located in the olfactory epithelium, a specialized tissue inside the nose that detects smells. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive the smell.

The OR3A4 gene encodes a protein that is specifically involved in the detection of certain odors. However, the exact odors that this protein can detect are not yet fully understood.

Structure[edit | edit source]

The OR3A4 protein is a G protein-coupled receptor, which means it has a specific structure that allows it to bind to odor molecules and trigger a signal. This structure includes seven transmembrane domains, which span the cell membrane, and an extracellular domain, which is exposed to the outside of the cell and can bind to odor molecules.

Clinical significance[edit | edit source]

While the exact role of the OR3A4 gene in human health and disease is not yet fully understood, it is thought that variations in this gene could potentially affect a person's sense of smell. For example, mutations in this gene could potentially lead to a reduced ability to smell certain odors.

See also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD