OR4A47

From WikiMD's Food, Medicine & Wellness Encyclopedia

OR4A47 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are responsible for detecting molecules in the environment and subsequently initiating a neuronal response. The olfactory receptor proteins interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.

Function[edit | edit source]

The olfactory receptor family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. The function of OR4A47 is not yet fully understood, but it is believed to play a crucial role in our sense of smell.

Structure[edit | edit source]

The OR4A47 gene is located on chromosome 11, specifically at 11q11. It spans a length of approximately 1.1 kilobases and consists of a single exon. The OR4A47 protein is a member of the Class A rhodopsin-like family of G protein-coupled receptors.

Clinical Significance[edit | edit source]

While the exact role of OR4A47 in disease is not yet fully understood, olfactory receptors in general have been implicated in a variety of diseases, including Parkinson's disease, Alzheimer's disease, and certain types of cancer. Further research is needed to determine the specific role of OR4A47 in these and other conditions.

See Also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD