OR4C13

OR4C13 is a gene that encodes a protein in humans. It is part of the olfactory receptor family, a group of genes that are involved in the detection of smell. The OR4C13 gene is located on chromosome 11.

Function

The OR4C13 gene is part of the olfactory receptor family, which is responsible for the detection of smell. These receptors are located in the olfactory epithelium, a small area in the back of the nose. When an odor molecule binds to an olfactory receptor, it triggers a nerve impulse that is sent to the brain, where it is interpreted as a specific smell.

Structure

The OR4C13 gene is located on chromosome 11, specifically on the long arm at position 11q11. It spans approximately 1 kilobase and contains one exon. The encoded protein is a member of the G protein-coupled receptor family, which are integral membrane proteins that possess seven transmembrane domains.

Clinical significance

While the exact role of OR4C13 in human health and disease is not fully understood, olfactory receptors in general are known to play a crucial role in the sense of smell. Loss of function mutations in these genes can lead to anosmia, a condition characterized by the inability to perceive odor.

Research

Research into the OR4C13 gene and its associated protein is ongoing. Understanding the function and structure of this gene could provide insights into the complex process of olfaction and potentially lead to treatments for conditions such as anosmia.

See also

• Olfactory receptor
• Anosmia
• Chromosome 11