OR4D6

OR4D6 also known as Olfactory Receptor Family 4 Subfamily D Member 6 is a protein that in humans is encoded by the OR4D6 gene. The protein encoded by this gene is a member of the olfactory receptor family. Olfactory receptors are G protein-coupled receptors involved in the detection of smell.

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.

Gene

The OR4D6 gene is located on chromosome 11, specifically 11p15.4. The gene spans approximately 1 kilobase and consists of a single coding exon. The exact function of OR4D6 is not known, but it is thought to be involved in the detection of specific odors.

Clinical significance

While the exact function of OR4D6 is not known, mutations in this gene have been associated with a reduced sense of smell, known as anosmia. Further research is needed to understand the role of OR4D6 in olfaction and potential links to disease.

See also

• Olfactory receptor
• Anosmia
• G protein-coupled receptor

External links

• OR4D6 at NCBI
• OR4D6 at GeneCards

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