OR4F3
OR4F3 is a gene that encodes the olfactory receptor, family 4, subfamily F, member 3. It is a protein-coding gene. Diseases associated with OR4F3 include anosmia, which is the inability to perceive odor or a lack of functioning olfaction.
Function[edit | edit source]
The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Clinical significance[edit | edit source]
Variations in this gene have been associated with differences in olfactory perception such as sensitivity to specific odors or olfactory threshold.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- OR4F3 at the National Center for Biotechnology Information
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