OR4K17
OR4K17 is a gene that encodes a protein in humans. It is also known as olfactory receptor, family 4, subfamily K, member 17. The OR4K17 gene is part of the olfactory receptor gene family, which is the largest gene family in the genome. The family members are G-protein coupled receptors that respond to smell and taste stimuli and are divided into a large number of subfamilies.
Function[edit | edit source]
The OR4K17 gene is thought to encode a G protein-coupled receptor that is involved in the detection of smell. The exact function of this gene is not yet fully understood, but it is believed to play a crucial role in the olfactory system.
Structure[edit | edit source]
The OR4K17 gene is located on chromosome 14q11.1 and is composed of 1 exon. The encoded protein is a member of the GPCR superfamily, which is characterized by seven transmembrane domains, an extracellular N terminus, and an intracellular C terminus.
Clinical Significance[edit | edit source]
While the exact role of OR4K17 in human health and disease is not yet fully understood, olfactory receptors in general have been implicated in a variety of diseases, including Parkinson's disease, Alzheimer's disease, and certain types of cancer. Further research is needed to determine the specific role of OR4K17 in these and other conditions.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD